Who we are

The Biotechnology Group is one of the largest business units in SGC. Doug Cossar manages the Biotechnology and Core Services Group. It has a staff of fifteen.

The group's core activities can be categorized as:

Research Services:

1. Supplying DNA clones for SGC targets

2. Cloning genes in our vectors using the high throughput method (HTP)

3. Performing test expression on generated expression constructs to assess the quantity and solubility of recombinant protein products using E. coli, eukaryotic cells or in vitro.

4. Executing additional studies e.g., protein - protein interactions to enable protein crystallization

5. Innovating techniques and adapting technologies for protein expression, purification, and crystallization.

Facility Support Services:

1. General Laboratory maintenance

2. Procurement of equipment and supplies

3. Health and Safety assurance and compliance

How we are organized

Doug Cossar operates as Biotechnology Group Manager and SGC Laboratory Manager. The group leverages the intellectual capital of scientific experts in the fields of molecular biology and biochemistry. Its fifteen (15) staff is organized into seven specialized subunits as detailed below:

Database Research:
Ivona Kozieradzki

Cloning:
Jocelyne Lew, M.Sc., Laboratory Technician
Elena Dobrovetsky, M.Sc., Laboratory Technician
Yanjun Li, M.Sc., Laboratory Technician
Farrell MacKenzie, M.Sc., Laboratory Technician

Test Expression, NMR, Protein Purification:
Hui Quang, Research Associate
Lissete Crombet, M.Sc., Laboratory Technician

Novel Methodologies:
Ivona Kozieradzki
Peter Loppnau, M.Sc., Laboratory Technician

Protein Expression in Insect Cells:
Alma Seitova, Research Associate
Hao He, Postdoc Fellow

Crystallization Trials:
Mani Ravichandran, M.Sc., Laboratory Technician
Joanna Kania, Research Assistant

Core Services:
Ronit Andorn Broza, M.Sc., Laboratory Technician
Rita Kilis, Research Assistant
Chris Glogowski, Research Assistant
Daniela Valeva, Research Assistant

Publications from the group