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Crystallography
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Select PublicationsWernimont AK, Amani M, Qiu W, Pizarro JC, Artz JD, Lin YH, Lew J, Hutchinson A, Hui R (2011) Structures of parasitic CDPK domains point to a common mechanism of activation. Proteins 79:803-20 Wernimont AK, Artz JD, Finerty P Jr, Lin YH, Amani M, Allali-Hassani A, Senisterra G, Vedadi M, Tempel W, Mackenzie F, Chau I, Lourido S, Sibley LD, Hui R. (2010) Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium Nat Struct Mol Biol. 17:596-601 Himanen JP, Yermekbayeva L, Janes PW, Walker JR, Xu K, Atapattu L, Rajashankar KR, Mensinga A, Lackmann M, Nikolov DB, Dhe-Paganon S (2010) Architecture of Eph receptor clusters PNAS 107:10860-5 Tempel W, Wu H, Dombrovsky L, Zeng H, Loppnau P, Zhu H, Plotnikov AN, Bochkarev A (2009) An intact SAM-dependent methyltransferase fold is encoded by the human endothelin-converting enzyme-2 gene Proteins. 74:789-93 Wernimont A, Edwards A (2009) In situ proteolysis to generate crystals for structure determination: an update. PLoS One. 4:e5094 Tempel W, Tong Y, Dimov S, Bochkarev A, Park H (2008) First crystallographic models of human TBC domains in the context of a family-wide structural analysis. Proteins. 71:497-502 Avvakumov GV, Walker JR, Xue S, Li Y, Duan S, Bronner C, Arrowsmith CH, Dhe-Paganon S (2008) Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1. Nature. 455:822-5 Bochkarev A, Tempel W. (2008) High throughput crystallography at SGC Toronto: an overview. Methods Mol Biol. 426:515-21 Dong A, Xu X, Edwards AM et al. (2007) In situ proteolysis for protein crystallization and structure determination. Nat Methods.41019-21 Allali-Hassani A, Pan PW, Dombrovski L, Najmanovich R, Tempel W, Dong A, Loppnau P, Martin F, Thornton J, Edwards AM, Bochkarev A, Plotnikov AN, Vedadi M, Arrowsmith CH. (2007): Structural and chemical profiling of the human cytosolic sulfotransferases. PLoS Biol., 5(2):e23. Useful Crystallographic Software
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