CLK1 with bound pyridoquinazoline inhibitor

Target ID:

CLK1A

Deposition Date:

Saturday 15th December 2018

Families:

Protein Kinase/CMGC

Related Diseases:

Signalling and cancer

Structure type:

protein-ligand

Download Coordinates:

Authors:

Schroeder, M., Tazarki, H., Zeinyeh, W., Esvan, Y.J., Khiari, J., Joesselin, B., Bach, S., Ruchaud, S., Anizon, F., Giraud, F., Moreau, P., Knapp, S., Structural Genomics Consortium (SGC)

Site:

Frankfurt

6Q8K

tabs

References

New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis.

Tazarki, H., Zeinyeh, W., Esvan, Y.J., Knapp, S., Chatterjee, D., Schroder, M., Joerger, A.C., Khiari, J., Josselin, B., Baratte, B., Bach, S., Ruchaud, S., Anizon, F., Giraud, F., Moreau, P.

(2019) Eur J Med Chem 166: 304-317

PubMed: 30731399