Xiang-Jiao Yang Ph.D.
Goodman Cancer Centre
McGill University
Xiang-Jiao Yang is currently an associate professor, Department of Medicine and a member of Goodman Cancer Center, McGill University, Montréal, Québec. He received PhD from Shanghai Institute of Biochemistry in 1990 and then moved to the National Institutes of Health (NIH) for postdoctoral training. Along with mentor Dr. Pat Nakatani, Dr Yang made a significant contribution to identification of PCAF as the first mammalian histone acetyltransferase in 1996. He joined McGill University as an assistant professor in 1997, received a Harold E Johns award from the National Cancer Institute of Canada in 2002, became tenured at McGill in 2003, and is now up for full professor promotion. His laboratory has been actively involved in identifying and characterizing different histone acetyltransferases and deacetylases. In addition, he and his colleagues have recently studied how protein lysine acetylation interplays with other post-translational modifications and forms dynamic intramolecular signaling programs for coordinated regulation of transcription factor function.
Talk Title: “Function and regulation of protein lysine acetyltransferases and deacetylases”