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The SGC Toronto scientists seek to determine the 3D structures
of human proteins of therapeutic relevance to diseases such as cancer
and diabetes metabolic disorders.
We have a particular focus on proteins involved in intracellular small molecule metabolism,
enzymes involved in the transfer of methyl, acetyl and Ubiquitin-like groups, proteases
and nucleotide triphosphatases.
We are also investigating proteins from Plasmodium falciparum (and its apicomplexan relatives)
which causes malaria.
The SGC Toronto laboratories, under the direction of
Prof. Cheryl Arrowsmith,
are housed within the Faculty of Medicine at the University of Toronto
and located in the heart of cosmopolitan Toronto.
Scientists at SGC Toronto are affiliated with several University Departments
including the Banting and Best Department of Medical Research,
the Departments of Physiology, Pharmacology, Medical Biophysics,
and Medical Genetics and Microbiology.
The SGC Toronto laboratories have research efforts in biotechnology,
laboratory automation, protein expression, protein crystallization
and X-ray crystallography.
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