[SGC Toronto Structures]

May 10th-14th, 2011 - SGC Toronto is hosting the next conference of the International Structural Genomics Organization

March 31st 2010 - The BBC highlights an SGC Toronto structure published in the journal Nature with new inhibitors to treat sleeping sickness. read

February 15, 2010 - Chemical & Engineering News covers SGC Toronto's work to characterise novel activators of Pyruvate Kinase M2 read

Encoded Library Technology: a new approach to ligand discovery
Dr. Barry A. Morgan
Vice President and Site Head
Molecular Discovery Research, GSK, Boston
January 28, 2010, 1:30 p.m.
SGC Toronto - 4th Floor Seminar Room

Epigenetic Mechanisms in Health and Disease
October 22 - 23, 2009
MaRS Center Auditorium, 101 College St., Toronto
Click here for the Symposium Website

SGC expression clones are now available from Open Biosystems/Thermo Scientific

Small Molecule Screening Workshop at SGC Toronto - March 5-6th and July 9-10th, 2009 (Download workshop material)

The SGC and the OICR jointly host the Symposium on Chemical Biology-Based Drug Design, Toronto, November 10th 2008

SGC Toronto has moved to its new location in MaRS as of Oct., 1st 2008:
The Structural Genomics Consortium
MaRS Centre, South Tower
101 College St., Suite 700
Toronto ON M5G 1L7

The SGC Toronto scientists seek to determine the 3D structures of human proteins of therapeutic relevance to diseases such as cancer and diabetes metabolic disorders. We have a particular focus on proteins involved in intracellular small molecule metabolism, enzymes involved in the transfer of methyl, acetyl and Ubiquitin-like groups, proteases and nucleotide triphosphatases. We are also investigating proteins from Plasmodium falciparum (and its apicomplexan relatives) which causes malaria.

The SGC Toronto laboratories, under the direction of Prof. Cheryl Arrowsmith, are housed within the Faculty of Medicine at the University of Toronto and located in the heart of cosmopolitan Toronto. Scientists at SGC Toronto are affiliated with several University Departments including the Banting and Best Department of Medical Research, the Departments of Physiology, Pharmacology, Medical Biophysics, and Medical Genetics and Microbiology.

The SGC Toronto laboratories have research efforts in biotechnology, laboratory automation, protein expression, protein crystallization and X-ray crystallography.

The SGC encourages collaborations with laboratories from across the globe on proteins that are currently on our target list. In addition, scientists from Ontario can nominate protein targets of pharmaceutical or biomedical relevance via the Ontario Genomics Institute. Nominated targets should be human proteins or proteins from human parasites for which a 3D protein structure will aid biomedical research. Download target nomination form here.

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